| Autor: |
M, Gottschalk, J, Bauer, B, Wohlgemuth, R, Rogos |
| Jazyk: |
němčina |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete. 46(10-11) |
| ISSN: |
0044-2542 |
| Popis: |
The contractility of human gallbladders without calculi of 10 patients with typical biliary pain was investigated in vivo (n = 7; pharmacosonography) and in vitro (n = 10; isometric registration). In 6 out of 7 cases, investigated in vivo as well as in vitro, the contractility was identical--therefore the smooth-muscle-preparation in the organ-bath could be an interesting model for studies with CCK-antagonists. 3 of the in-vitro-preparations showed hypomotility consecutive to acetylcholine- and CCK-stimulation. Histologically, the destruction of the normal gallbladder wall structure by scars, chronic inflammation and the evidence of so-called Rokitansky-Aschoff-sinuses could be proved. The importance of these findings probably causal to the process of cholelithogenesis is discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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