| Autor: |
Tayana Silva, de Carvalho, Alódia, Brasil, Luana K R, Leão, Danielle Valente, Braga, Mateus, Santos-Silva, Nadyme, Assad, Waldo Lucas, Luz, Evander de Jesus O, Batista, Gilmara de Nazareth Tavares, Bastos, Karen Renata Matos Herculano, Oliveira, Domingos Luiz Wanderley Picanço, Diniz, Anderson Manoel, Herculano |
| Rok vydání: |
2022 |
| Zdroj: |
Foodnutrition research. 66 |
| ISSN: |
1654-661X |
| Popis: |
Açaí (Euterpe oleracea) has a rich nutritional composition, showing nutraceutical and protective effects in several organs. In this study, the effects of an açaí-enriched diet on motor performance, anxiety-like behavior, and memory retention were deeply investigated.Eight-week male Wistar rats were fed with an Euterpe oleracea (EO) pulp-enriched diet, an olive oil-enriched (OO) diet (polyunsaturated fatty acid [PUFA] fat control diet), or a chow diet for 31 days (28 days pre-treatment and 3 days during behavioral tests). Afterward, animals were submitted to a battery of behavioral tests to evaluate spontaneous motor behavior (open-field test), anxiety-like behavior (elevated plus maze and open-field test), and memory retention (step-down). Oxidative stress in the hippocampus was evaluated by a lipid peroxidation assay.EO-enriched diet did not influence the body weight and food intake but increased the glucose plasmatic level after 31 days under this diet. However, a similar fat-enriched diet stimulated a marked weight gain and reduced the food intake, followed by changes in the plasmatic lipid markers. EO-enriched diet preserved the motor spontaneous performance, increased the exploration in the aversive environment (anxiolytic-like effects), and elevated the latency to step-down (improved memory retention). The EO-enriched diet also reduced the level of lipid peroxidation in the hippocampus. These positive effects of EO-enriched diet can greatly support the usage of this diet as a preventive therapy.Taken together, the current study suggests that Euterpe oleracea-enriched diet promotes anxiolytic-like effects and improves memory consolidation, possibly due to the reduced levels of lipid peroxidation in the hippocampus. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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