| Autor: |
Julia L, Ober-Blöbaum, Daniela, Ortner, Bernhard, Haid, Anna, Brand, Christoph, Tripp, Björn E, Clausen, Patrizia, Stoitzner |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Methods in molecular biology (Clifton, N.J.). 1559 |
| ISSN: |
1940-6029 |
| Popis: |
Skin dendritic cells (DC) are strategically positioned at the body's second largest epithelial border to the environment. Hence they are the first antigen presenting cells that encounter invading pathogens and environmental antigens, including contact sensitizers and carcinogens penetrating the skin. Moreover, DC have the unique ability to induce immunity or tolerance and thus take center stage in regulating innate and adaptive immune responses. Skin DC can be divided into several phenotypically and functionally distinct subtypes. The three main subsets are Langerin |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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