Hypercholesterolemia in young adult APOE

Autor:	Renata, Martins Cardoso, Eline, Creemers, Samira, Absalah, Gert S, Gooris, Menno, Hoekstra, Miranda, Van Eck, Joke A, Bouwstra
Rok vydání:	2018
Předmět:	Mice Apolipoproteins E Receptors LDL Fatty Acids Hypercholesterolemia Animals Epidermis Lipids Permeability Apolipoproteins B
Zdroj:	Biochimica et biophysica acta. Molecular and cell biology of lipids. 1864(7)
ISSN:	1879-2618
Popis:	Long-term exposure to hypercholesterolemia induces the development of skin xanthoma's characterized by the accumulation of lipid-laden foam cells in humans and in mice. Early skin changes in response to hypercholesterolemia are however unknown. In this study, we investigated the skin lipid composition and associated barrier function in young adult low-density lipoprotein receptor knockout (LDLR
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::84c39cca286482a6472ade1051860dbb https://pubmed.ncbi.nlm.nih.gov/30905828 Zobrazit plný text záznamu Full Text from ScienceDirect