Development of immortalized human articular cartilage cell lines

Autor: G, Verbruggen, A M, Malfait, K F, Almqvist, E M, Veys, S, Thenet, B, Benoit, S, Demignot, A, Tachet des Combes, M, Adolphe
Rok vydání: 1993
Předmět:
Zdroj: Agents and actions. Supplements. 39
ISSN: 0379-0363
Popis: Human articular cartilage cells were transfected with the t.-sensitive polyomavirus large T antigen of SV40. Several immortalized chondrocyte cell lines were obtained. The types of acidic polysaccharides and of collagen synthesized suggest dedifferentiation in the in vitro culture system used afterwards to obtain large numbers of cells.
Databáze: OpenAIRE