Matching the reaction-diffusion simulation to dynamic [

Autor:	Kuangyu, Shi, Christine, Bayer, Florian C, Gaertner, Sabrina T, Astner, Jan J, Wilkens, Fridtjof, Nüsslin, Peter, Vaupel, Sibylle I, Ziegler
Rok vydání:	2017
Předmět:	Mice Nude Models Biological Diffusion Oxygen Mice Cell Transformation Neoplastic Head and Neck Neoplasms Cell Line Tumor Positron-Emission Tomography Image Interpretation Computer-Assisted Tumor Microenvironment Animals Humans Tumor Hypoxia Female Neoplasms Squamous Cell Misonidazole
Zdroj:	Physiological measurement. 38(2)
ISSN:	1361-6579
Popis:	Positron-emission tomography (PET) with hypoxia specific tracers provides a noninvasive method to assess the tumor oxygenation status. Reaction-diffusion models have advantages in revealing the quantitative relation between in vivo imaging and the tumor microenvironment. However, there is no quantitative comparison of the simulation results with the real PET measurements yet. The lack of experimental support hampers further applications of computational simulation models. This study aims to compare the simulation results with a preclinical [
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::84584c23b7fa35e554bc5cc32ac53fe1 https://pubmed.ncbi.nlm.nih.gov/28055983 Zobrazit plný text záznamu