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OBJECTIVE: To analyse the efficacy of the intervention with a calendar reminder of the medication taking in the treatment of the hyperlipidemias. DESIGN: Controlled, randomised clinical trial. SETTING: Twelve clinics at 5 primary care centres, Spain. PARTICIPANTS: Two hundred and twenty people diagnosed with hypercholesterolaemia according to Spanish Consensus criteria were chosen. INTERVENTION: Two groups were formed. The control group (CG) of 110 patients, who received the doctor's normal treatment; and the Intervention group (IG) of 110 patients, who received in addition a calendar remider of medication taking. MAIN MEASUREMENTS: Meausured of compliance was performed by moniotrs electronic (MEMS) and cholesterol, triglycerides, HDL-C, and LDL-C determined at the start, and at the third and sixth months. Percentages of patients complying (80%-110%), the mean compliance percentage and the degree of control were compared. The reduction of absolute and relative risk (RAR and RRR) and the mean number of people that required an intervention in order to avoid non-compliance (NI) were calculated. RESULTS: One hundred and eighty eight people (85.45%) completed the survey, 96 in the IG and 92 in the CG; 26.55% were non compliers with the therapy (CI, ±6.3%) (IG, 10.5%, CI, ±4.6%; CG, 42.6%, CI, ±10.1% [P |
