Thioredoxin reductase from

Autor: Junxin, Xue, Wei, Jiang, Yongjun, Chen, Fengju, Gong, Minyan, Wang, Peng, Zeng, Can, Xia, Quan, Wang, Kehe, Huang
Rok vydání: 2017
Předmět:
Zdroj: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(10)
ISSN: 1530-6860
Popis: Thioredoxin reductase (TR) can help pathogens resist oxidative-burst injury from host immune cells by maintaining a thioredoxin-reduction state during NADPH consumption. TR is a necessary virulence factor that enables the persistent infection of some parasites. We performed bioinformatics analyses and biochemical assays to characterize the activity, subcellular localization, and genetic ablation of
Databáze: OpenAIRE