Brominated polyacetylenes from the Philippines sponge Diplastrella sp

Autor:	Melissa L, Lerch, Mary Kay, Harper, D John, Faulkner
Rok vydání:	2003
Předmět:	Inhibitory Concentration 50 Molecular Structure Acetylene Polymers Philippines Electron Spin Resonance Spectroscopy Animals Polyynes HIV Integrase Inhibitors Hydrocarbons Brominated Porifera
Zdroj:	Journal of natural products. 66(5)
ISSN:	0163-3864
Popis:	Five novel brominated polyacetylenic diols, diplynes A-E (2-6), and three sulfated analogues, diplyne A 1-sulfate (7), diplyne C 1-sulfate (8), and 2-deoxydiplyne D sulfate (9), were isolated from the Philippines sponge Diplastrella sp. by employing bioassay-guided fractionation using the HIV-1 integrase inhibition assay. The novel metabolites were characterized by interpretation of spectroscopic data.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8423521145e83e894dcf763222099a00 https://pubmed.ncbi.nlm.nih.gov/12762803 Zobrazit plný text záznamu