| Autor: |
R N, Befidi-Mengue, R C, Ratard, A, D'Alessandro, J, Rice, R, Befidi-Mengue, L E, Kouemeni, B L, Cline |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
The Journal of tropical medicine and hygiene. 95(6) |
| ISSN: |
0022-5304 |
| Popis: |
Our objective was to determine in a Cameroonian school population the effect of mild to moderate S. haematobium infection intensity on growth and development of children before and 6 months after praziquantel treatment. Previous studies have yielded contradictory results. Children from Bertoua schools were divided into four study groups: heavily infected (500 eggs 10 ml-1), moderately infected (1-499 eggs 10 ml-1) treated with praziquantel, a similar group treated with placebo, and an uninfected control group. Anthropometric measures--height for age per cent median (HAPM), and weight for age per cent median (WAPM)--were significantly higher among the uninfected children. Stepwise regression analysis showed that S. haematobium and Ascaris infections were the strongest predictors of the HAPM with hookworm and malaria infections playing a lesser role. Post treatment comparison of the praziquantel treatment group and the placebo group showed no significant differences for the anthropometric indicators except for mid-arm circumference. Longer observations of growth after treatment as well as monitoring of the rate of reinfection would be necessary to understand better the effect of S. haematobium on growth. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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