Superoxide dismutase-like activity of 1,2,3-triazole derivatives

Autor:	G, Biagi, O, Livi, G L, Ramacciotti, V, Scartoni, L, Bazzichi, M R, Mazzoni, A, Lucacchini
Rok vydání:	1990
Předmět:	Chemistry Magnetic Resonance Spectroscopy Chemical Phenomena Chemistry Physical Superoxide Dismutase Nitroblue Tetrazolium Anti-Inflammatory Agents Non-Steroidal Penicillamine Triazoles Oxidation-Reduction
Zdroj:	Farmaco (Societa chimica italiana : 1989). 45(1)
ISSN:	0014-827X
Popis:	This paper reports the synthesis of some sulfurated 1,2,3-triazole derivatives and the biological evaluation, for the superoxide dismutase-like activity, of these new compounds together with several 1,2,3-triazoles previously described by us. All the compounds possess a SOD-like activity and some of them showed an activity equivalent to or higher than those of penicillamine or thiopronin, which are well known therapeutic drugs in the treatment of rheumatoid arthritis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::839747d8b70617594c63a45cabf13b84 https://pubmed.ncbi.nlm.nih.gov/2337447 Zobrazit plný text záznamu