Hopea odorata Extract Can Efficiently Kill Breast Cancer Cells and Cancer Stem-Like Cells in Three-Dimensional Culture More Than in Monolayer Cell Culture

Autor: Nhan Lu-Chinh, Phan, Khuong Duy, Pham, Phong, Le Minh, Mai Thi-Thanh, Nguyen, Ngoc Phan, Kim, Kiet Dinh, Truong, Phuc, Van Pham
Rok vydání: 2020
Předmět:
Zdroj: Advances in experimental medicine and biology. 1292
ISSN: 0065-2598
Popis: The breast cancer cells with CD44HO-MeOH-E was produced from Hopea odorata plant. The VN9 breast cancer cells (VN9) were collected and expanded from the previous study. The breast cancer stem-like cells (VN9CSC) were sorted from the VN9 based on phenotype CD44The results showed that HO-MeOH-E was sensitive to both VN9 and VN9CSC in 3D more than 2D culture (ICTaken these results, HO-MeOH-E has the potential effect in hypoxia-activated chemotherapy specifically on breast cancer stem-like cells with CD44
Databáze: OpenAIRE