[Acute myocardial infarction in Iceland 1982-1983. Prognosis and risk factors in the pre-thrombolytic era.]

Autor: U, Agnarsson, N, Sigfusson, I I, Gudmundsdottir, I, Stefansdottir
Rok vydání: 2010
Zdroj: Laeknabladid. 82(4)
ISSN: 0023-7213
Popis: This nationwide study describes the short- and longterm outcome of acute myocardial infarction in Iceland 1982-83 prior to the routine use of aspirin and thrombolytic therapy. The material consists of 486 cases of acute myocardial infarction, 390 men and 96 women aged 25-64 years. Death prior to hospitalization occured in 124 cases but hospital treatment was given to 287 men and 75 women. Evidence of a previous myocardial infarction was found in 22%. An anterior myocardial infarction was present in 29% and an inferior myocardial infarction was present in 31%. The 28 day mortality was 12.4% but the long-term mortality over a mean of 7.1 year was 35.9%. The principal determinants of the risk of death in both sexes were ST-segmentelevation on admission ECG with a relative risk of 1.78, the use of digitalis and diuretics prior to the onset of an acute myocardial infarction with a relative risk of 1.89 and 1.72. Those treated with inotrophics in hospital had a relative risk of 2.81 but patients treated with anticoagulants in hospital had an improved prognosis with a relative risk of 0.45 but nitrates and b-blockers did not affect the outcome.
Databáze: OpenAIRE