[Surveillance of acute flaccid paralysis in Belarus]
| Autor: | E O, Samoĭlovich, M A, Ermolovich, I F, Kotova, E Iu, Svirchevskaia, V P, Shimanovich, A K, Kozhemiakin, I I, Protas, E V, Fel'dman |
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| Rok vydání: | 2007 |
| Předmět: |
Republic of Belarus
Incidence Vaccination Administration Oral Coxsackievirus Infections Genome Viral Myelitis Antibodies Viral Guillain-Barre Syndrome Enterovirus B Human Poliovirus Poliovirus Vaccine Inactivated Neuritis Species Specificity Risk Factors Case-Control Studies Poliovirus Vaccine Oral Acute Disease Humans Muscle Hypotonia Paralysis Sentinel Surveillance Poliomyelitis |
| Zdroj: | Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2) |
| ISSN: | 0372-9311 |
| Popis: | The ten-years experience of acute flaccid paralysis (AFP) surveillance in Belarus has been summarized. Among 456 AFP cases reported from 1996 to 2005, 11 were classified as vaccine-associated paralytic poliomyelitis (VAPP), 445--as non-polio AFP. The risk of VAPP for the period 1996-2001 was 1 case per 745,000 used doses of oral poliovaccine (OPV). For the recipients of OPV the risk was 1 case per 911,700 doses and for the first-dose recipients--1 case per 96,000 doses. The high incidence of VAPP was a reason for implementation of sequential polio vaccination schedule in 2000. Guillain-Barre syndrome dominated among non-polio AFP (39.3% of cases); more rare were traumatic neuritis (27.9% of cases), transient monoparalysis (12.1%), myelitis (7.6%). Non-polio AFP differed from VAPP by following epidemiological and virological characteristics: predominance of previously repeatedly vaccinated against poliomyelitis; development of paralysis in long-term period after vaccination; isolation of non-polio viruses belonged to three serotypes of Coxsackie B viruses (B1, B4, B6) and six serotypes of Echo viruses (6, 7, 11, 14, 24, 25) in 8.1% of cases; absence of typical for polio residual paralyses in patients who excreted vaccine polioviruses. |
| Databáze: | OpenAIRE |
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