| Autor: |
R V, Petrov, L V, Koval'chuk, A R, Kalinina, A S, Pavliuk, T Iu, Ul'ianova |
| Rok vydání: |
1989 |
| Předmět: |
|
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 107(6) |
| ISSN: |
0365-9615 |
| Popis: |
The methodological aspects of Lak-cells functional activity test were determined. NK-resistance of P-815 culture cells and NK-sensitive K-562 cells were used as target cells. The highest cytotoxicity level was registered at the 5-th day of culturing MNC with rIL-2 at the final concentration (100 U/ml). The method developed was used for testing healthy donors group and group of patients with IL-2 dependent immunodeficiency (ophthalmic herpes). Data obtained show the significant decrease of LAK-cells functional activity of patients in comparison with healthy donors. Thus, the developed method is recommended for complex estimation of immune status of patients with IL-2-dependent immuno deficiency. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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