| Autor: |
T, Meskhi, D, Khachidze, Sh, Barbakadze, G, Madzhagaladze, M, Gorgoshidze, D, Monaselidze, T, Lezhava, N, Tadumadze |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Biofizika. 49(6) |
| ISSN: |
0006-3029 |
| Popis: |
It was shown that chromatin contained in human lymphocytes has two stages of denaturation: with T(d)VII = 94.4 degrees C, Q(d)VII = 50.8 J/g DNA, and T(d)VIII = 105.1 degrees C Q(d)VIII = 44.9 J/g DNA. The peptide bioregulator prostamax causes a redistribution of heat among endotherms T(d)III and T(d)IV and a shift of both endotherms to low temperatures by 2.9 and 1.0 degrees C, respectively. It was supposed that the redistribution of heat among endotherms is connected with a partial relaxation of the 30-nm-thick fiber in the 10-nm filament. A weak decrease in T(d)VIII and T(d)VII of lymphocytes treated with prostamax compared to untreated ones is connected with small structural changes of nucleosomal organization in the 10-nm filament and 30-nm-thick fiber. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
