[Effect of eprosartan on left ventricular diastolic function and cerebral hemodynamics in patients with hypertension]
| Autor: | L I, Markova, A E, Radzevich, V V, Koren'kov, N I, Belavina, N A, Griabina, O Iu, Zharova |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Time Factors Ultrasonography Doppler Transcranial Imidazoles Models Cardiovascular Thiophenes Middle Aged Ventricular Function Left Treatment Outcome Acrylates Diastole Echocardiography Cerebrovascular Circulation Hypertension Homeostasis Humans Female Antihypertensive Agents Carotid Artery Internal Vertebral Artery Follow-Up Studies |
| Zdroj: | Kardiologiia. 42(10) |
| ISSN: | 0022-9040 |
| Popis: | Eprosartan (600-1200 mg/day) was given for 4 weeks to 28 patients aged 32-62 years with stage II-III hypertension (WHO, 1999). Left ventricular diastolic function and cerebral blood flow were assessed by echocardiography and ultrasound dopplerography. Treatment with eprosartan was associated with improvements of impaired left ventricular diastolic function, structural and functional state of the heart, venous outflow from cerebral vessels, and restoration of unpaired autoregulation of cerebral blood flow. All these phenomena could potentially lead to normalization of cerebral tissue perfusion and stabilization of cerebral blood flow. |
| Databáze: | OpenAIRE |
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