[Potentially bioactive pyrimidine derivatives. 1. 2-Amino-4-aryl-8-arylidene-3,4,5,6,7,8-hexahydroquinazoline]
| Autor: | J, Deli, T, Lóránd, D, Szabó, A, Földesi |
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| Jazyk: | němčina |
| Rok vydání: | 1984 |
| Předmět: | |
| Zdroj: | Die Pharmazie. 39(8) |
| ISSN: | 0031-7144 |
| Popis: | Six condensed 2-amino-4-arylpyrimidines (1a-f) were synthesized by the base catalyzed reaction of some monoarylidenecycloalkanones and guanidine. The reaction of 2,6-diarylidenecyclohexanones with guanidine yielded 2-amino-4-aryl-3,4,5,6,7,8-hexahydroquinazolines which were stable only as salts 3a-j. The oxidation of 3a-j led to 2-amino-4-aryl-8-arylidene-5,6,7,8-tetrahydroquinazolines 4a-j. |
| Databáze: | OpenAIRE |
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