| Autor: |
N M, Kurhaliuk, O V, Ikkert, L S, Vovkanych, O V, Horyn', M O, Hal'kiv, S K, Hordiĭ |
| Rok vydání: |
2002 |
| Předmět: |
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| Zdroj: |
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 73(5) |
| Popis: |
The effect of L-arginine and blockator of nitric oxide synthase L-NNA on processes of calcium mitochondrial capacity in liver with different resistance to hypoxia in the experiments with Wistar rats has been studied using the followrng substrates of energy support: succinic, alpha-ketoglutaric acids, alpha-ketolutarate and inhibitor succinatedehydrogenase malonate. As well we used substrates mixtures combination providing for activation of aminotransferase mechanism: glutamate and piruvate, glutamate and malate. It has been shown that L-arginine injection increases calcium mitochondrial capacity of low resistant rats using as substrates the succinate and alpha-ketoglutarate to control meanings of high resistance rats. Effects of donors nitric oxide on this processes limit NO-synthase inhibitor L-NNA. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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