| Autor: |
Z, Brada, N H, Altman, M, Hill, S, Bulba |
| Rok vydání: |
1982 |
| Předmět: |
|
| Zdroj: |
Research communications in chemical pathology and pharmacology. 38(1) |
| ISSN: |
0034-5164 |
| Popis: |
Female Wistar rats were fed a semisynthetic diet containing 0.3% DL-ethionine for 52 weeks and, most of them bearing hepatocellular carcinomas, were switched to a basal diet for one week and then received 80 mg DL-methionine per rat (cir. 25 mg/100 g body wt) by gavage once per day, five times a week, over a period of 13 weeks. Methionine treatment significantly affected progression of hepatic tumors induced by DL-ethionine administration. The frequency of rats with hepatocellular carcinomas in the methionine treated group was significantly lower than that in control groups. It therefore appears that methionine treatment resulted in a remission of the malignant process. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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