| Autor: |
M E, Ragozzino, C, Wilcox, M, Raso, R P, Kesner |
| Rok vydání: |
1999 |
| Předmět: |
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| Zdroj: |
Behavioral neuroscience. 113(1) |
| ISSN: |
0735-7044 |
| Popis: |
The present study examined whether inactivation of the prelimbic-infralimbic areas or the dorsal anterior cingulate area impairs strategy switching in the cheeseboard task. After implantation of a cannula aimed at either the prelimbic-infralimbic or dorsal anterior cingulate areas, all rats were tested in a spatial and a visual-cued version of the task. Some of the rats received the spatial version first, followed by the visual-cued version. The procedure for the other rats was reversed. Infusions of 2% tetracaine into the prelimbic-infralimbic or dorsal anterior cingulate areas did not impair acquisition of the spatial or visual-cued versions. However, inactivation of the prelimbic-infralimbic areas, but not the dorsal anterior cingulate area, impaired learning when rats were switched from one version to the other. These findings suggest that the prelimbic-infralimbic areas are involved in switching to new behavior-guiding strategies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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