[A case of disseminated carcinomatosis of the bone marrow with disseminated intravascular coagulation caused by advanced colon cancer successfully treated with SOX/bevacizumab]
| Autor: | Hiroaki, Suzuki, Nobuko, Matsuoka, Yuki, Ushimaru, Yoshihito, Kakimoto, Akira, Toyoda, Yoshitake, Endo, Osamu, Murakami, Yasuro, Kato, Masafumi, Inoue, Takuya, Kimura, Yasuo, Matsuda, Hiroshi, Sasakabe |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Organoplatinum Compounds Disseminated Intravascular Coagulation Middle Aged Antibodies Monoclonal Humanized Bevacizumab Oxaliplatin Drug Combinations Oxonic Acid Fatal Outcome Chemotherapy Adjuvant Antineoplastic Combined Chemotherapy Protocols Colonic Neoplasms Humans Bone Marrow Neoplasms Tegafur |
| Zdroj: | Gan to kagaku ryoho. Cancerchemotherapy. 41(8) |
| ISSN: | 0385-0684 |
| Popis: | Our patient was a 58-year-old man who was diagnosed with a large bowel obstruction caused by ascending colon cancer, together with multiple liver metastases for which a right hemicolectomy was performed. After the operation, he developed disseminated intravascular coagulation(DIC)and severe anemia. Bone marrow biopsy findings led to a diagnosis of disseminated carcinomatosis of the bone marrow caused by colon cancer. We administered S-1+oxaliplatin(SOX) and bevacizumab( BV)chemotherapy, which improved the DIC. The patient was discharged from the hospital. After a total of six courses of chemotherapy, the carcinoma became resistant. We changed the drug regimen and his clinical condition improved. He survived for 292 days from the onset of disease. |
| Databáze: | OpenAIRE |
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