Nifedipine preparations on the Belgian market: a comparative study

Autor:	K, De Braekeleer, C, Fierens, J, Corthout
Rok vydání:	2010
Předmět:	Food-Drug Interactions Belgium Nifedipine Solubility Delayed-Action Preparations Biological Availability Reproducibility of Results Capsules Spectrophotometry Ultraviolet Calcium Channel Blockers Chromatography High Pressure Liquid Drug Utilization Tablets
Zdroj:	Journal de pharmacie de Belgique. (4)
ISSN:	0047-2166
Popis:	Nifedipine preparations formulated as immediate-release capsules and prolonged-release tablets were evaluated with different tests, including in vitro dissolution, assay and content uniformity, and determination of related compounds. The analytical methods were previously validated according to international guidelines. All examined products complied with the postulated requirements but the dissolution test for prolonged-release tablets showed that these products cannot be interchanged.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::817d7dbf876d00a7bbdce5f0485b1d92 https://pubmed.ncbi.nlm.nih.gov/20183991 Zobrazit plný text záznamu