| Autor: |
Dinesh, Kannabhiran, Matthew J, Everly, Jennifer K, Walker-McDermott, Sue, Tiongko, Rex, Friedlander, Prabhakar, Putheti, Vijay, Sharma, Darshana, Dadhania |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Clinical transplants. |
| ISSN: |
0890-9016 |
| Popis: |
The predominant anti-HLA IgG subclass during antibody mediated rejection episodes is IgG1. Class I DSA IgG subclasses respond to single cycle of bortezomib-based therapy more frequently as compared to Class II DSA IgG subclasses. High titer Class II DSA IgG subclasses are less likely to respond to single cycle bortezomib-based therapy. Future studies are needed to determine if the response to bortezomib-based therapy is dependent on the type of DSA and/or the strength of the DSA at the time of antibody mediated rejection episode. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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