[Interaction between benzene and toluene in long term inhalation exposure in rats (author's transl)]

Autor: D, Gradiski, P, Bonnet, P, Duprat, D, Zissu, J L, Magadur, J P, Guenier
Jazyk: francouzština
Rok vydání: 1981
Předmět:
Zdroj: Toxicological European research. Recherche europeenne en toxicologie. 3(4)
ISSN: 0249-6402
Popis: Industrial chemicals are seldom used as pure substances; hazards resulting from exposure to mixtures have, however not been solved. Our study deals with chronic inhalation toxicity of a mixture of benzene and toluene; few studies have been completed on this subject. Our results show: - leucopenia with benzene alone, at a concentration of 50 p.p.m., that is not detectable in the presence of toluene; - metabolic variations consisting in: a decrease in the phenol urinary rate versus time with benzene alone; a sharp decrease of this rate from the third month of exposure on, in presence of toluene.
Databáze: OpenAIRE