| Autor: |
G B, Naff, S W, Hedrick, W D, Ratnoff, M A, Novak, M C, Smith, C, Steiner, E W, Todd |
| Rok vydání: |
1980 |
| Předmět: |
|
| Zdroj: |
Journal of immunology (Baltimore, Md. : 1950). 124(6) |
| ISSN: |
0022-1767 |
| Popis: |
Pure preparations of rabbit properdin were obtained from rabbit serum by ion-exchange chromatography. These preparations functioned as properdin when they were measured with the zymosan assay or with a serum reagent selectively depleted of properdin by a specific immunoabsorbent. Properdin in these preparations was in its activated state. A new serum factor was required to measure properdin activity when purified preparations of rabbit properdin were tested with the zymosan assay. This factor was designated as ZBP, or zymosan-binding protein. ZBP appeared to be distinct from known components of the alternative complement pathway and the classical complement system, and it did not appear to be an immunoglobulin. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
