Genetic Predictors of Change in Episodic Verbal Memory by Cognitive Intervention

Autor: Pedro, Montejo Carrasco, David, Prada Crespo, María Luisa, Delgado Losada, Christian, Montejo Rubio, Mercedes, Montenegro-Peña
Rok vydání: 2021
Předmět:
Zdroj: Journal of integrative neuroscience. 21(4)
ISSN: 0219-6352
Popis: Cognitive interventions (CIs) in the elderly are activities that seek to improve cognitive performance and delay its deterioration. Our objectives were to study potential genetic predictors of how a CI program may influence immediate and delayed episodic verbal memory (EVM).162 participants were elderly individuals without dementia who were randomized into parallel control and experimental groups. Participants underwent genetic testing to analyze theWe found the CI was associated with improvements in several cognitive functions, including immediate and delayed EVM. While no individual gene was associated with any such change, the interaction betweenOur study shows that the participants' genotype can have an impact on the results of CIs. Cognitive stress may stimulate the interaction of various genes and as such, different types of CI should be established for distinct groups of people taking into account the individual's characteristics, like genotype, to improve the results of this type of health prevention and promotion activity.
Databáze: OpenAIRE