Diagnosis of heterozygotes in Glanzmann's thrombasthenia

Autor:	H, Stormorken, G O, Gogstad, N O, Solum, H, Pande
Rok vydání:	1982
Předmět:	Adult Blood Platelets Male Platelet Function Tests Genetic Carrier Screening Fibrinogen Platelet Membrane Glycoproteins Middle Aged Child Preschool Animals Humans Female Blood Coagulation Tests Blood Platelet Disorders Rabbits Child Immunoelectrophoresis Two-Dimensional Serum Albumin Glycoproteins
Zdroj:	Thrombosis and haemostasis. 48(2)
ISSN:	0340-6245
Popis:	A study of a family with a propositus suffering from classical thrombasthenia type I has shown that the new immunochemical methods detect heterozygotes with high reliability. There was no overlapping between heterozygotes and normals, and the concentration of the glycoproteins IIb-IIIa-complex is remarkable constant around 50-60% in the heterozygotes. Furthermore, heterozygotes as a group show an increased bleeding tendency.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::80b3a617e4efbce00d14e357251e2dbc https://pubmed.ncbi.nlm.nih.gov/6217584 Zobrazit plný text záznamu