| Popis: |
Experimental spinal cord trauma was performed intraoperatively in 132 rabbits (Allen's method modified by Faden et al.). Only 77 animals were administered drugs (glucocorticoids, antioxidants and anti-inflammatory nonsteroids): Prednisolon, Fluocinolon-N-spray, Epurox, Ketazone, Rheopyrin and Rengasil. The remaining 55 animals were controls. Results were clinically (the assessment of lower limb movement was performed on a 5-score scale) and neuropathologically studied. From a clinical point of view, Prednisolon, Fluocinolon and Rengasil showed some beneficial effects. No significant differences of nervous fibre regeneration were noticed between probands and controls. |
