| Autor: |
Cláudio W, Canal, Matheus N, Weber, Samuel P, Cibulski, Mariana S, Silva, Daniela E, Puhl, Hanspeter, Stalder, Ernst, Peterhans |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
BioMed Research International |
| ISSN: |
2314-6141 |
| Popis: |
Hepatitis C virus (HCV) (genus Hepacivirus; family Flaviviridae) is a major human pathogen causing persistent infection and hepatic injury. Recently, emerging HCV-like viruses were described infecting wild animals, such as bats and rodents, and domestic animals, including dogs, horses, and cattle. Using degenerate primers for detecting bovine pestiviruses in a 1996 survey three bovine serum samples showed a low identity with the genus Pestivirus of the Flaviviridae family. A virus could not be isolated in cell culture. The description of bovine hepaciviruses (BovHepV) in 2015 allowed us to retrospectively identify the sequences as BovHepV, with a 88.9% nucleotide identity. In a reconstructed phylogenetic tree, the Brazilian BovHepV samples grouped within the bovine HCV-like cluster in a separated terminal node that was more closely related to the putative bovine Hepacivirus common ancestor than to bovine hepaciviruses detected in Europe and Africa. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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