Using Oral and Colon Cancer Cells for Studying the Anticancer Properties of Antimicrobial Peptides

Autor: Teerakul, Arpornsuwan, Wimolpak, Sriwai, Hathaitip, Sritanaudomchai, Sittiruk, Roytrakul
Rok vydání: 2016
Předmět:
Zdroj: Methods in molecular biology (Clifton, N.J.). 1548
ISSN: 1940-6029
Popis: Antimicrobial peptides (AMPs) are of importance in defense mechanism of many organisms and are potential candidate for treatment of infections in animals and humans. AMPs exhibit a wide range of immunomodulatory activities related to innate immunity, wound healing, and inflammation. AMPs also serve as drug delivery vectors, antitumor agents, and mitogenic agents. Here, we describe the investigation of anticancer and cytotoxic activities of antimicrobial peptides by colorimetric MTT assay using smooth muscle, dental pulp stem cell, human colon cancer cell line (SW620), and human oral squamous carcinoma cell line (HSC4).
Databáze: OpenAIRE