Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F

Autor:	Varsha G, Desai, Taewon, Lee, Carrie L, Moland, Vikrant, Vijay, Tao, Han, Sherry M, Lewis, Eugene H, Herman, James C, Fuscoe
Rok vydání:	2018
Předmět:	Male Proteomics Antibiotics Antineoplastic Proteome Myocardium Heart Protective Agents Risk Assessment Cardiotoxicity Mice Doxorubicin von Willebrand Factor Animals Administration Intravenous Dexrazoxane Receptor Notch1 Biomarkers
Zdroj:	Toxicology and applied pharmacology. 363
ISSN:	1096-0333
Popis:	Cardiotoxicity is a serious adverse effect of doxorubicin (DOX) treatment in cancer patients. Currently, there is a lack of sensitive biomarkers to predict the risk of DOX-induced cardiotoxicity. Using SOMAmer-based proteomic technology, 1129 proteins were profiled to identify potential early biomarkers of cardiotoxicity in plasma from male B6C3F
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::7f5582af9862da1f7860ced0b2a5c8ae https://pubmed.ncbi.nlm.nih.gov/30517846 Zobrazit plný text záznamu Full Text from ScienceDirect