[Follicular penetration. An important pathway for topically applied substances]

Autor:	J, Lademann, N, Otberg, H, Richter, U, Jacobi, H, Schaefer, U, Blume-Peytavi, W, Sterry
Jazyk:	němčina
Rok vydání:	2003
Předmět:	Microscopy Curcumin Lasers Skin Absorption Administration Cutaneous Permeability Ointments Sebum Microscopy Electron Microscopy Fluorescence Humans Emulsions Cyanoacrylates Epidermis Coloring Agents Hair Follicle Tomography Hair
Zdroj:	Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 54(4)
ISSN:	0017-8470
Popis:	The knowledge of penetration pathways in and through the skin is a prerequisite for the development and optimization of topically applied drugs and cosmetics. Skin penetration has been assumed to occur via diffusion though the lipid domains of the stratum corneum. Recent studies show that the skin appendages, especially the hair follicles, play an important role in skin penetration processes. Topically applied substances cannot enter all follicles. We discuss the reasons for the phenomenon of open and closed hair follicles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::7f16e85bd3ff401112b8f54c2ca0d6d2 https://pubmed.ncbi.nlm.nih.gov/12669202 Zobrazit plný text záznamu Full text from SpringerLink