[In vivo induction of antigenic modulation in man by an anti-T cell monoclonal antibody (author's transl)]

Autor: L, Chatenoud, M, Baudrihaye, J, Schindler, H, Kreis, G, Goldstein, J F, Bach
Jazyk: francouzština
Rok vydání: 1982
Předmět:
Zdroj: Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie. 294(16)
ISSN: 0249-6313
Popis: The anti-T cell monoclonal antibody OKT3 was administered to renal allograft recipients. A dramatic depletion of peripheral T cells was immediately observed followed, after 2-5 days, by the reappearance of a limited but significant number of or OKT3-4+ or OKT3-8+T cells showing antigenic modulation of the OKT3-defined antigen. These cells recovered the OKT3 receptor after overnight in vitro incubation.
Databáze: OpenAIRE