[MRI-assisted brachytherapy of nonresectable liver metastases. Preliminary technical and clinical experiences]

Autor: J, Kettenbach, B, Pokrajac, S, Schamp, C, Fellner, R, Schmid, B, Gustorff, J, Berger, M, Grgurin, K, Peer, U, Wolff, W, Seitz, R, Pötter, J, Lammer
Jazyk: němčina
Rok vydání: 2001
Předmět:
Zdroj: Der Radiologe. 41(1)
ISSN: 0033-832X
Popis: To evaluate the feasibility and efficacy of MR-guided interstitial brachytherapy of non-resectable liver metastasis.Liver metastases (0.8-5.2 cm in diameter) were treated during a prospective phase I/II study using an open 0.2 Tesla MR system (Magnetom Open Viva, Siemens, Erlangen). MR-compatible brachytherapy applicators were placed percutaneously under MR-guidance in an open 0.2 Tesla MR system (Magnetom Open Viva, Siemens, Erlangen) using fast T1-weighted sequences. Pretreatment and follow-up studies were performed using a 1.5 Tesla MR system.Preliminary results of an unpublished prospective study are discussed exemplary on 2 selected patients. The median procedure time was 4.9 h. No major complications were observed and late effects were acceptable. In large symptomatic metastases only a temporary relief of pain was achieved. In smaller metastases (DM 3 cm) a tumor control was observed.MR-guided brachytherapy is feasible and has the potential to ablate liver metastases with diameter of less than 3 cm. Further developments are necessary.
Databáze: OpenAIRE