| Popis: |
The clinical characterisation of polycystic ovary syndrome (PCOS) and its fenotype complicate the search for its genetic causes. Still now, there is no concordance about the exact clinical phenotype for PCOS and there is still an open question whether polycystic ovaries are the necessary part of PCOS at all. Therefore, the author suggests to accept and follow Legro's proposal and genetic models in the future investigations of PCOS. Through the ethnic, familial cluster studies, through molecular genetic examinations and novel technology, we may be able to solve the problem of PCOS and find it out, how much the PCOS could be connected with mutations in human genome and how much could be the importance of environmental factors in PCOS. |
