[Poorly differentiated neuroendocrine small-cell carcinoma of the gallbladder]
| Autor: | M, Benkel, F, Brasch, J D, Neumann, A, Altendorf-Hofmann, W, Sendt |
|---|---|
| Jazyk: | němčina |
| Rok vydání: | 2011 |
| Předmět: |
Male
Palliative Care Synaptophysin Gallbladder CD56 Antigen Neuroendocrine Tumors Lymphatic Metastasis Biomarkers Tumor Hepatectomy Humans Lymph Node Excision Cholecystectomy Gallbladder Neoplasms Carcinoma Small Cell Neoplasm Recurrence Local Tomography X-Ray Computed Aged Neoplasm Staging Ultrasonography |
| Zdroj: | Zentralblatt fur Chirurgie. 137(1) |
| ISSN: | 1438-9592 |
| Popis: | Neuroendocrine tumours of the gastroenteropancreatic system (GEP-NETs) are rare, in particular those of the gallbladder. Due to the limited therapeutic options, surgical resection is favoured.Described below is the case of a 69-year-old male with a lymphogenically metastasising, poorly differentiated neuroendocrine carcinoma of the gallbladder who presented with unspecific abdominal pain.Following complete surgical resection of the tumour and the lymph node metastases he developed a recurrence 6 weeks post-operatively. The recurrence was treated with chemotherapy. Re-staging after three courses, however, showed further tumour progression. Prior to the start of a second-line treatment the patient died 13 weeks after surgery.This case demonstrates the complexity of this rare disease with diagnosis in advanced tumour stage and poor prognosis. |
| Databáze: | OpenAIRE |
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