| Autor: |
Kenta, Tanaka, Mami, Kishimoto, Yosuke, Asada, Yuta, Tanaka, Yujiro, Hoshino, Kiyoshi, Honda |
| Rok vydání: |
2019 |
| Zdroj: |
The Journal of organic chemistry. 84(21) |
| ISSN: |
1520-6904 |
| Popis: |
We report the one-pot synthesis of 2,2-disubstituted chromanes with electron-withdrawing substituents. This reaction provides a simple yet efficient route to a wide range of electron-deficient chromanes in high yield and excellent regioselectivity. The reaction of salicylaldehyde with 1,1-disubstituted ethylenes smoothly furnishes these electron-deficient chromanes, which can be further transformed into functionalized chromanes or chromene. For example |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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