| Autor: |
Mónica, García-Alvarez, Fernando, Chaves, Francisca, Sanz, Joaquín R, Otero |
| Rok vydání: |
2006 |
| Předmět: |
|
| Zdroj: |
Enfermedades infecciosas y microbiologia clinica. 24(2) |
| ISSN: |
0213-005X |
| Popis: |
During 2003, an increase in the number of cases of listeriosis was observed in a tertiary hospital in Madrid. The objectives of this study were to review the clinical characteristics of the cases diagnosed from 2001 to 2003 and to investigate clonal relationships among the clinical isolates of Listeria monocytogenes.A retrospective analysis was performed of all cases of listeriosis diagnosed in Hospital 12 de Octubre (Madrid) during 2001-2003. Clinical records for each patient were reviewed and all clinical isolates were compared using serotyping and pulsed-field gel electrophoresis (PFGE) with the AscI and SmaI restriction enzymes.A total of 18 patients were diagnosed: 4 in 2001, 2 in 2002, and 12 in 2003. The estimated incidence rates were 7.3 cases per 1,000,000 inhabitants in 2001, 3.6 in 2002 and 21.8 in 2003. The most frequent serotype during the study period was 4b (66.7%), and this serotype represented 83.3% of the cases diagnosed in 2003. PFGE yielded 12 different genotypes; one of them (PFGE type G) was common to 5 cases diagnosed in 2003.The expansion of a single clone of L. monocytogenes during 2003 partially contributed to increasing the incidence of listeriosis that year. Molecular epidemiology techniques are useful for detecting outbreaks of a possible foodborne origin and their results should promote epidemiological studies to investigate the food products involved. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
