Discrimination between sialic acid linkage modes using sialyllactose-imprinted polymers

Autor: Liliia, Mavliutova, Bruna, Munoz Aldeguer, Jesper, Wiklander, Celina, Wierzbicka, Chau Minh, Huynh, Ian A, Nicholls, Knut, Irgum, Börje, Sellergren
Rok vydání: 2021
Zdroj: RSC advances. 11(36)
ISSN: 2046-2069
Popis: Glycosylation plays an important role in various pathological processes such as cancer. One key alteration in the glycosylation pattern correlated with cancer progression is an increased level as well as changes in the type of sialylation. Developing molecularly-imprinted polymers (MIPs) with high affinity for sialic acid able to distinguish different glycoforms such as sialic acid linkages is an important task which can help in early cancer diagnosis. Sialyllactose with α2,6'
Databáze: OpenAIRE