Analgesic and anti-inflammatory activity of the ethanolic extract from Spiranthera odoratissima A. St. Hillaire (Manacá) roots

Autor:	L G, Matos, I S, Pontes, L M F, Tresvenzol, J R, Paula, E A, Costa
Rok vydání:	2005
Předmět:	Male Analgesics Hot Temperature Dose-Response Relationship Drug Plant Extracts Anti-Inflammatory Agents Non-Steroidal Pain Peritonitis Carrageenan Plant Roots Rats Mice Cell Migration Inhibition Animals Rats Wistar Sleep Pentobarbital Rutaceae Acetic Acid Phytotherapy
Zdroj:	Phytotherapy research : PTR. 18(12)
ISSN:	0951-418X
Popis:	Acetic acid-induced abdominal writhing, the tail flick test and carrageenan-induced peritonitis were used to study the analgesic and anti-inflammatory activity of the crude ethanolic extract from Spiranthera odoratissima roots. Pentobarbital-induced sleeping time was used to study the central depressant effect of the extract. The ethanolic extract caused a dose dependent inhibition of acetic acid-induced abdominal writhing and leukocyte migration, and produced a significant, dose-related increase in the duration of sleep. The results suggest that Spiranthera odoratissima roots contain compounds with anti-inflammatory and central depressant actions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::7d47211e610efdfc56c1c73445192670 https://pubmed.ncbi.nlm.nih.gov/15742350 Zobrazit plný text záznamu Plný text