[Central nervous system granulocytic sarcoma after bone marrow transplant: case report]

Autor: Cláudio Esteves, Tatsui, Andrei, Koerbel, Daniel Monte-Serrat, Prevedello, João Candido, Araújo, Léo Fernando Silva, Ditzel, Luis Fernando, Bleggi-Torres
Rok vydání: 2002
Předmět:
Zdroj: Arquivos de neuro-psiquiatria. 60(3-B)
ISSN: 0004-282X
Popis: Granulocytic sarcoma is a solid tumor, composed by granulocytic precursor cells at various levels of differentiation, located at an extra-medullary site. It is associated with acute myeloid leukemia, and its presence reveals a bad prognostic factor. The treatment usually consists of radiotherapy and chemotherapy. A case of an intracranial granulocytic sarcoma occurring six months after a bone marrow transplant in a patient with acute myeloid leukemia is reported. The patient presented with headache and left hemiplegia caused by a large fronto-parietal lesion with significant mass effect. After a complete surgical resection there was a full recovery of the deficit. The patient completed radiotherapy and chemotherapy with no evidence of disease after three months of follow-up. Surgery is indicated in the presence of progressive neurological deficit. Surgical decompression may provide rapid improvement and therefore, affect quality of survival.
Databáze: OpenAIRE