Red blood cell-hitchhiking chitosan nanoparticles for prolonged blood circulation time of vitamin K

Autor: Yuli, Wang, Chaoyang, Zhou, Yaning, Ding, Mengyu, Liu, Zhongjia, Tai, Qian, Jin, Yang, Yang, Zhiping, Li, Meiyan, Yang, Wei, Gong, Chunsheng, Gao
Rok vydání: 2020
Předmět:
Zdroj: International journal of pharmaceutics. 592
ISSN: 1873-3476
Popis: Nanocarriers have been extensively applied for intravascular drug delivery. However, rapid clearance from circulation by mononuclear phagocyte system has limited their applications. Erythrocytes carriers are potential solutions to overcome the limitations of nanocarriers and considered to be ideal natural carriers for drug delivery because of their unique properties. The purpose of this work is to combine nanocarriers with erythrocytes carriers for sustained release and prolonged circulation time of vitamin K
Databáze: OpenAIRE