Optimization of the reduction of

Autor: Zita, Oláh, Andreas T J, Vogg, Tibor, Kremmer, Zoltán, Szűcs, Zoltán, Varga, Rita, Dóczi
Rok vydání: 2018
Zdroj: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 149
ISSN: 1872-9800
Popis: The radiochemical separation of n.c.a. arsenic on its own or for radio-labelling purposes usually involves the issue of reducing arsenic(V). Numerous approaches for reducing pentavalent arsenic have been examined. A novel HPLC method has also been presented for accessing the efficiency of the reduction in terms of *As(III)/*As(V). Labelling with trivalent radioarsenic seems to be a promising research field to access new radiopharmaceuticals, for example, using arsenic as a surrogate for phosphorus. Moreover, as a model system, the labelling reaction of *As(III) with dihydrolipoic acid has been systematically optimized.
Databáze: OpenAIRE