Combined androgen and antimetabolite therapy of advanced female breast cancer. A report of the cooperative breast cancer group

Autor: I S, Goldenberg, N, Sedransk, H, Volk, A, Segaloff, R M, Kelley, C R, Haines
Rok vydání: 1975
Předmět:
Zdroj: Cancer. 36(2)
ISSN: 0008-543X
Popis: A clinical trial of androgen and antimetabolite therapy of advanced female breast cancer was conducted in 110 patients by the Cooperative Breast Cancer Group. An objective regression rate of 20% was achieved in women receiving oral testolactone, 6% in patients given intravenous fluorouracil alone, and 14% when the androgen and antimetabolite were administered together. This randomized trial according to the CBCG protocol did not produce the high regression rate noted previously in a nonrandomized, nonprotocol evaluation of these drugs.
Databáze: OpenAIRE
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