| Autor: |
T, Kato, H, Nishimura, J, Umezu, S, Takeuchi, K, Kanazawa, H, Inoue, M, Suzuki, M, Hirono, T, Suzuki, H, Okajima |
| Rok vydání: |
1985 |
| Předmět: |
|
| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 12(10) |
| ISSN: |
0385-0684 |
| Popis: |
We conducted a joint phase II study in 76 patients with gynecological cancer (42 patients with ovarian cancer, 22 patients with cervical cancer, 10 patients with endometrial cancer and 2 patients with vaginal cancer). The response rate was 25.0% in the patients with ovarian cancer, 13.3% in those with cervical cancer, and 28.6% in those with endometrial cancer. The overall response rate was 23.1%. When the patients were classified according to dose schedules, the highest response rate was obtained in the group administered THP-ADM at a dose of 60 mg per body by single i.v. injection at 3-week intervals. Such side effects as myelosuppression and gastrointestinal disturbances were observed, but alopecia, a marked side-effect of ADM administration, was mild, and no cardiac toxicity was seen in any of the patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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