| Autor: |
Juno, Van Valkenburgh, Marlon Vincent V, Duro, Erica, Burnham, Quan, Chen, Shaowei, Wang, Jenny, Tran, Bilal E, Kerman, Sung Hee, Hwang, Xiaodan, Liu, Naomi S, Sta Maria, Francesca, Zanderigo, Etienne, Croteau, Stanley I, Rapoport, Stephen C, Cunnane, Russell E, Jacobs, Hussein N, Yassine, Kai, Chen |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Prostaglandins, leukotrienes, and essential fatty acids. 186 |
| ISSN: |
1532-2823 |
| Popis: |
Dysreglulated brain arachidonic acid (AA) metabolism is involved in chronic inflammation and is influenced by apolipoprotein E4 (APOE4) genotype, the strongest genetic risk factor of late-onset Alzheimer's disease (AD). Visualization of AA uptake and distribution in the brain can offer insight into neuroinflammation and AD pathogenesis. Here we present a novel synthesis and radiosynthesis of 20-[ |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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