| Autor: |
K J, Steenkamp, W, Duim, M S, Myer, S C, Malfeld, R, Anderson |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 85(12) |
| ISSN: |
0256-9574 |
| Popis: |
Two different acetylcholine receptor (AChR) preparations derived from amputated human muscle (AChRAMP) and from the human rhabdomyosarcoma cell line TE671 (AChRTE671) were compared in radio-immunoprecipitation assays for the detection of AChR auto-antibodies in serum specimens from 20 patients with proven myasthenia gravis. Tests performed with the AChRTE671 and AChRAMP antigen preparations were positive in all the patients and in 19/20 respectively. A high degree of correlation (r = 0.94) was evident between the two auto-antigen preparations. Assays based on the use of TE671-derived antigen represent a useful alternative to the conventional assay using AChRAMP for the detection of AChR auto-antibodies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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