Oxidative state and zona-binding ability in mouse spermatozoa treated with reduced glutathione

Autor: Kaoruko, Mizuno, Shuji, Hirata, Tsuyoshi, Kasai, Seiichiro, Nagai, Shoji, Ohta, Kazuhiko, Hoshi
Rok vydání: 2018
Předmět:
Zdroj: Reproductive medicine and biology. 1(2)
ISSN: 1445-5781
Popis: Background and Aims: Nuclear proteins in mature mammalian spermatozoa nuclei are oxidized to form numerous disulfide bonds. Reduced glutathione (GSH) in the oocyte has been linked to spermatozoan nuclear decondensation after fertilization. In this study, we analyzed whether GSH reduced protamines in sperm nuclei in vitro, and examined the zona‐binding ability of treated nuclei.
Databáze: OpenAIRE