[Toxoplasmosis and cytomegalovirus serology in patients infected with HIV in Congo]
| Autor: | M, Makuwa, H, Loemba, J, Ngouonimba, Y, Beuzit, J P, Louis, J M, Livrozet |
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| Jazyk: | francouzština |
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male AIDS-Related Opportunistic Infections Adolescent Antibodies Protozoan Cytomegalovirus Middle Aged Antibodies Viral Sensitivity and Specificity Congo Seroepidemiologic Studies Immunoglobulin G Population Surveillance Toxoplasmosis Cerebral Cytomegalovirus Infections HIV-1 Prevalence Animals Humans Female Toxoplasma Biomarkers Aged |
| Zdroj: | Sante (Montrouge, France). 4(1) |
| ISSN: | 1157-5999 |
| Popis: | Cerebral toxoplasmosis and cytomegalovirus (CMV) infection are very frequent in AIDS. Biological markers of toxoplasmosis and CMV were studied in blood and cerebrospinal fluid (CSF) of 121 HIV-positive and 35 HIV-negative patients in the Central Hospital of the Congolese Army in Brazzaville. In the case of clinically suspected cerebral toxoplasmosis, the simultaneous presence of specific IgG antibodies in the blood and in the CSF can be considered as having complementary diagnostic value (PPV = 63.3%, NPV = 89.9%). The symptomatology of AIDS is very polymorphous and includes various etiological factors; as a result it is very difficult to estimate the responsibility of cytomegalovirus in the absence of positive viral culture, even with the simultaneous presence of specific IgG antibodies in the blood and CSF (PPV = 75.7%, NPV = 54.6%). |
| Databáze: | OpenAIRE |
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